Transgenic Mouse Facility, University Park
Produces transgenic and gene-targeted (knockout) mice for the Penn State research community.
Services
1. Transgenic mouse production
2. Gene-targeted (knockout) mouse production
(production of targeted mutant mice by embryonic stem cell microinjection)
3. Other services
- Consulting: project design, construct design, screening assays, protocols, positive and negative selection schemes, any aspect of a project (no fee)
- Special projects: inducible promoters, Cre recombinase- LoxP2
- Special mouse strains may be considered
- Isolation of DNA from mouse tail clips (minimum 10/procedure)
- Isolation of DNA from embryonic stem cell clones (minimum 50/procedure)
- Breeding of PI selected chimera or transgenic founders
- Expansion of embryonic stem cell line(s) and arrangements for MAP testing
- In vivo embryo rederivation (live male).
- In vivo embryo rederivation (cryopreserved embryos).
- Technical training (hourly rate)
Fees
Please contact us for details of fees. Fees are subject to change if mouse pricing or husbandry charges increase.