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Transgenic Mouse Facility, University Park

Produces transgenic and gene-targeted (knockout) mice for the Penn State research community.

Services

1. Transgenic mouse production

2. Gene-targeted (knockout) mouse production

2-cell stage(production of targeted mutant mice by embryonic stem cell microinjection)

3. Other services

  • Consulting: project design, construct design, screening assays, protocols, positive and negative selection schemes, any aspect of a project (no fee)
  • Special projects: inducible promoters, Cre recombinase- LoxP2
  • Special mouse strains may be considered
  • Isolation of DNA from mouse tail clips (minimum 10/procedure)
  • Isolation of DNA from embryonic stem cell clones (minimum 50/procedure)
  • Breeding of PI selected chimera or transgenic founders
  • Expansion of embryonic stem cell line(s) and arrangements for MAP testing
  • In vivo embryo rederivation (live male).
  • In vivo embryo rederivation (cryopreserved embryos).
  • Technical training (hourly rate)

Fees

Please contact us for details of fees. Fees are subject to change if mouse pricing or husbandry charges increase.